Background: Pembrolizumab demonstrated clinically meaningful and durable antitumor activity with a manageable safety profile in recurrent/metastatic (R/M) cutaneous squamous cell carcinoma (cSCC). Patients and methods: KEYNOTE-629 was a global, open-label, nonrandomized, phase II trial of patients with locally advanced (LA) or R/M cSCC conducted at 59 centers.. The incidence of non-melanoma skin cancers, including cutaneous squamous cell carcinoma (CSCC), in Australia and New Zealand is among the highest in the world, with age-standardised incidence rates of 229.2 per 100 000 men and 66.7 per 100 000 women. 1 Most people with CSCC present with local disease and can be cured; for those with advanced disease, however, median overall survival time is.
Squamous cell carcinoma Skin Cancer 909
Development of cutaneous squamous cell carcinoma (cSCC) in a… Download Scientific Diagram
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Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer, which predominantly occurs on the head and neck. Early detection and treatment of primary tumours is crucial to limit progression and local invasion of deep tissues. While high-risk markers of poor prognosis have been identified, factors predicting regional.. Advanced cutaneous squamous-cell carcinoma is a condition that encompasses these two incurable situations, and patients with this condition are considered for palliative systemic therapy, which.
